Answer
We are here to know which of the following has primary responsibility for eliminating alcohol from the bloodstream? The liver is the main organ responsible for the elimination of alcohol from the bloodstream. Well, the alcohol metabolism and breakdown process takes place in several steps after alcohol enters the body. The same follows for the alcohol absorption in the body as multiple organs take part in this.
Right after consumption, the alcohol enters the digestive system and travels to the stomach where around 20% of the alcohol is absorbed. The remaining 80% of the alcohol is absorbed in the small intestine and then travels to the bloodstream. Once the blood is entered into the bloodstream, it travels through the entire body which is why the impact is seen almost everywhere.
Well, most of the alcohol ends up in the Liver which metabolizes the vast majority of the alcohol. The liver can process the alcohol from a standard drink in one hour.
Anything more than one ounce is excess for the liver, and the additional amount accumulates in the blood and several other tissues until it is metabolized. The saturation of alcohol in the blood is dangerous for the body as it develops damage to the brain and other cells.
Which Of The Following Has Primary Responsibility For Eliminating Alcohol From The Bloodstream?
On the other hand, studies conclude that the human body is pretty effective in processing alcohol and alcohol poisoning is not a common thing. Alcohol percentage in the bloodstream is measured by Blood Alcohol Content (BAC). It is the term used to express the presence of ethanol present in the unit mass of alcohol per volume.
Around 90 to 98% of consumed alcohol is absorbed and metabolized by the body whereas the remaining percentage is expelled through vomit, urine, sweat, and feces.
Coming to the function of the Liver, Ethanol is metabolized in 2 stages and the speed of this metabolism differs from one person to another.
In the first stage, an enzyme named alcohol Dehydrogenase which is present in the cytoplasm of liver cells is used. This enzyme fastens the alcohol oxidation and converts it into Acetaldehyde. The enzyme can oxidize alcohol when the alcohol binds to a site on it and loses some electrons as H atoms.
Well, for the oxidation to complete, a coenzyme is also required to ADH which helps it in taking one H atom from the released 2H. The metabolite formed in this process is called Acetaldehyde which is toxic and causes nausea, headaches, flushing, and many alcohol-related disorders.
Reason Behind Hangover
It is the main reason behind the hangover which most drunk people go through. Thus, it undergoes the second phase to reduce the side effects. The main second phase is to convert the metabolite i.e. acetaldehyde into acetic acid.
In this phase, another liver cell enzyme called Acetaldehyde Dehydrogenase (ALDH) is used to metabolize acetaldehyde into acetic acid. Acetic acid is inactive and can easily convert into CO2 and water.
Well, many people are unable to metabolize acetaldehyde as a result they feel sick for a long period. The main reason for this condition is a mutation that takes place in ALDH in mainly the East Asian Region. In this condition, the people get the side effects of alcohol pretty soon causing facial flushing, vomiting, nausea, and an increase in heart rate as well.
Furthermore, the metabolites from the second phase with the standard ALDH enzyme in the liver cells get out of the body easily. The standard way of acetic acid leaving the body is through sweat and urine.
If the consumed alcohol is within the standard amount, the person won’t even feel the hangover for a long time. Most persons with good liver cells and healthy enzymes can feel normal within an hour with a low alcohol-based drink.
Frequently Asked Questions
1. What is the primary responsibility for eliminating alcohol from the bloodstream?
The liver eliminates more than 90% of alcohol; 2-5% is excreted unchanged in urine, sweat, or breath. The first step involved in metabolism is oxidation by alcohol dehydrogenases. Out of that, at least four isoenzymes exist to acetaldehyde in the presence of cofactors.
2. What is responsible for removing alcohol from the bloodstream?
Five percent of the alcohol leaves the body through urine, sweat glands, and breathing. The liver must break down (metabolize) alcohol to remove it from the system. The liver metabolizes alcohol at a very constant rate, one drink per hour.
3. Where is alcohol eliminated from the blood primarily?
The liver is the main organ responsible for metabolizing ingested alcohol. Yet the stomach (i.e., gastric) ADH contributes to FPM.
4. What is the best way to reduce alcohol absorption?
Food is one of the best ways. That said, it is recommended to Always eat before drinking, especially foods high in protein. Food in your stomach will help slow the processing of alcohol. A person who has not eaten hits a peak BAC typically between 1/2 hour to two hours of drinking.
5. What food helps absorb alcohol?
A nutritious meal before drinking alcohol helps you avoid a hangover or getting too drunk. It’s suggested that you consume foods high in protein and healthy fats. The best ones to try are yogurt and salmon, which help slow alcohol absorption. Avocados and bananas with plenty of potassium might be lost after drinking.
6. Does drinking water reduce alcohol absorption?
A drunk person who wants to sober up can consume food if they can keep it down. Yes, they should drink water because it helps dilute the alcohol in the body. Food also plays a vital role in the manner that it helps to slow down the body’s alcohol absorption.
Final Words
The organ that has the primary responsibility for eliminating alcohol from the bloodstream is the liver,” yet there are additional organs working with it to fully eliminate it from the body.
